9 genetic interactions and 75 correlations retrieved

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Genetic interactions
Correlations

Negative genetic interactions

Query gene Array gene SGA score p-value
YPR178W - prp4-1, RNA4
Splicing factor, component of the U4/U6-U5 snRNP complex
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
-0.28 4.1e-04
YHR028C - DAP2, DPP2
Dipeptidyl aminopeptidase, synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
-0.21 5.0e-04
YLR193C - UPS1
Phosphatidic acid transfer protein; plays a role in phospholipid metabolism by transporting phosphatidic acid from the outer to the inner mitochondrial membrane; localizes to the mitochondrial intermembrane space; null mutant has altered cardiolipin and phosphatidic acid levels; ortholog of human PRELI
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
-0.19 1.3e-03
YLR423C - ATG17, APG17
Scaffold protein responsible for phagophore assembly site organization; regulatory subunit of an autophagy-specific complex that includes Atg1p and Atg13p; stimulates Atg1p kinase activity; human ortholog RB1CC1/FIP200 interacts with p53, which inhibits autophagy in human cells
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
-0.17 5.1e-03
YGR262C - BUD32, LDB14
Protein kinase, component of the EKC/KEOPS complex with Kae1p, Cgi121p, Pcc1p, and Gon7p; EKC/KEOPS complex is required for t6A tRNA modification and may have roles in telomere maintenance and transcription
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
-0.17 2.7e-03

Positive genetic interactions

Query gene Array gene SGA score p-value
YPL115C - BEM3
Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.15 9.0e-07
YBR060C - orc2-2, SIR5, RRR1
Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; interacts with Spp1p and with trimethylated histone H3; phosphorylated by Cdc28p
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.15 1.3e-04
YFL011W - HXT10
Putative hexose transporter, expressed at low levels and expression is repressed by glucose
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.14 7.2e-07
YPL038W - MET31
Zinc-finger DNA-binding transcription factor; involved in transcriptional regulation of the methionine biosynthetic genes; MET31 has a paralog, MET32, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.13 5.7e-03

Correlations

Gene 1 Gene 2 Correlation
YML035C - AMD1, AMD3
AMP deaminase; tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; thought to be involved in regulation of intracellular purine (adenine, guanine, and inosine) nucleotide pools
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.172
YAR050W - FLO1, FLO4, FLO2
Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.172
YMR226C - TMA29, TMA29
NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.169
YDR530C - APA2
Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II; AP4A phosphorylase involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; APA2 has a paralog, APA1, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.165
YLR070C - XYL2
Xylitol dehydrogenase, converts xylitol to D-xylulose; expression induced by xylose, even though this pentose sugar is not well utilized by S. cerevisiae; null mutant has cell wall defect
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.154
YNR024W - MPP6
Nuclear exosome-associated RNA binding protein; involved in surveillance of pre-rRNAs and pre-mRNAs, and the degradation of cryptic non-coding RNAs (ncRNA); copurifies with ribosomes
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.145
YDR015C - YDR015C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene HED1/YDR014W-A
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.144
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YPL223C - GRE1
Hydrophilin essential in dessication-rehydration process; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway
0.143
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YPL103C - FMP30
Mitochondrial inner membrane protein with a role in maintaining mitochondrial morphology and normal cardiolipin levels; proposed to be involved in N-acylethanolamine metabolism; related to mammalian N-acylPE-specific phospholipase D
0.141
YNL022C - YNL022C
Putative cytosine 5-methyltransferase, contains seven beta-strand methyltransferase motif similar to NOP2/YNL061W; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; predicted to be involved in ribosome biogenesis
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.136
YHR032W - YHR032W
Member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily; overproduction confers ethionine resistance and accumulation of S-adenosylmethionine
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.130
YML016C - PPZ1
Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance; PPZ1 has a paralog, PPZ2, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.130
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YOL141W - PPM2, TYW4
AdoMet-dependent tRNA methyltransferase also involved in methoxycarbonylation; required for the synthesis of wybutosine (yW), a modified guanosine found at the 3'-position adjacent to the anticodon of phe-tRNA; similarity to Ppm1p
0.130
YMR312W - ELP6, KTI4, TOT6, HAP3
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.129
YKL110C - KTI12, TOT4
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.129
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YPL102C - YPL102C
Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation enhances replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene ELP4
0.127
YML074C - FPR3, NPI46
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p; FPR3 has a paralog, FPR4, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.126
YGR023W - MTL1
Putative plasma membrane sensor; involved in cell integrity signaling and stress response during glucose starvation and oxidative stress; has structural and functional similarity to Mid2p; MTL1 has a paralog, MID2, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.125
YER152C - YER152C
Protein with 2-aminoadipate transaminase activity; shares amino acid similarity with the aminotransferases Aro8p and Aro9p; YER152C is not an essential gene
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.124
YIR037W - HYR1, ORP1, GPX3
Thiol peroxidase; functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor; HYR1 has a paralog, GPX1, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.123
YGR022C - YGR022C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF MTL1/YGR023W
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.122
YLL051C - FRE6
Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.122
YGR071C - YGR071C
Protein proposed to be involved in vacuolar functions; mutant shows defect in CPY processing and fragmented vacuoles; deletion mutant has increased glycogen accumulation and displays elongated buds; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; ENV11 has a paralog, VID22, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.120
YIL117C - PRM5
Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.120
YML032C - RAD52
Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.120
YNR020C - ATP23
Putative metalloprotease of the mitochondrial inner membrane, required for processing of Atp6p; has an additional role in assembly of the F0 sector of the F1F0 ATP synthase complex; substrate of the Mia40p-Erv1p disulfide relay system, and folding is assisted by Mia40p
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.119
YHR015W - MIP6
Putative RNA-binding protein; interacts with Mex67p, which is a component of the nuclear pore involved in nuclear mRNA export; MIP6 has a paralog, PES4, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.118
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YOR193W - PEX27
Peripheral peroxisomal membrane protein; involved in controlling peroxisome size and number, interacts with Pex25p; PEX27 has a paralog, PEX25, that arose from the whole genome duplication
0.117
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YOR080W - DIA2, YOR29-31
Origin-binding F-box protein; forms an SCF ubiquitin ligase complex with Skp1p and Cdc53p; plays a role in DNA replication; plays a role in transcription; required for correct assembly of RSC complex, correct RSC-mediated transcription regulation, and correct nucleosome positioning; involved in invasive and pseudohyphal growth; required to target Cdc6p for ubiquitin-mediated destruction during G1 phase
0.116
YER144C - UBP5
Putative ubiquitin-specific protease; concentrates at the bud neck; UBP5 has a paralog, DOA4, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.115
YMR192W - GYL1, APP2
Putative GTPase activating protein (GAP) with a role in exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; increases in abundance and relocalizes from bud neck to cytoplasm upon DNA replication stress; GYL1 has a paralog, GYP5, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.114
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YPL145C - KES1, BSR3, OSH4, LPI3
One of seven members of the yeast oxysterol binding protein family; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex; KES1 has a paralog, HES1, that arose from the whole genome duplication
0.114
YNL072W - RNH201, Rnh2A, RNH35
Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis and errant ribonucleotides misincorporated during DNA replication; homolog of RNAse HI; related to human AGS4 which causes Aicardi-Goutieres syndrome
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.113
YGL043W - DST1, SII, S-II, TFIIS, P37, PPR2
General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.113
YMR225C - MRPL44, YmL44, YMR44
Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.113
YMR271C - URA10
Minor orotate phosphoribosyltransferase (OPRTase) isozyme; catalyzes the fifth enzymatic step in the de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; URA10 has a paralog, URA5, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.113
YDR057W - YOS9
ER quality-control lectin; integral subunit of the HRD ligase; binds to glycans with terminal alpha-1,6 linked mannose on misfolded N-glycosylated proteins and participates in targeting proteins to ERAD; member of the OS-9 protein family
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.112
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YOR172W - YRM1
Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes
0.112
YDL050C - YDL050C
Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.111
YIL162W - SUC2
Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.111
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YOR012W - YOR012W
Putative protein of unknown function
0.111
YKL163W - PIR3, CCW8
O-glycosylated covalently-bound cell wall protein; required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway; PIR3 has a paralog, HSP150, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.110
YMR006C - PLB2
Phospholipase B (lysophospholipase) involved in lipid metabolism; displays transacylase activity in vitro; overproduction confers resistance to lysophosphatidylcholine
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.110
YMR306C-A - YMR306C_A
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.110
YCR015C - YCR015C
Putative protein of unknown function; YCR015C is not an essential gene
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.110
YJL115W - ASF1, CIA1
Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.110
YLR384C - IKI3, KTI7, TOT1, ELP1
Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; maintains structural integrity of Elongator; homolog of human IKAP, mutations in which cause familial dysautonomia (FD)
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.110
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YOR091W - TMA46, RBF46
Protein of unknown function that associates with translating ribosomes; interacts with GTPase Rbg1p
0.110
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YPL086C - ELP3, KAT9, KTI8, TOT3, HPA1
Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin
0.110
YDR535C - YDR535C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YDR535C is not an essential gene.
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.109
YKL191W - DPH2
Protein required, along with Dph1p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Kti11p
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.108
YMR099C - YMR099C
Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase), likely involved in carbohydrate metabolism; GFP-fusion protein localizes to both the nucleus and cytoplasm and is induced in response to the DNA-damaging agent MMS
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.108
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YPR065W - ROX1, REO1
Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance
0.108
YGR025W - YGR025W
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.107
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YPR193C - HPA2, KAT10
Tetrameric histone acetyltransferase with similarity to Gcn5p, Hat1p, Elp3p, and Hpa3p; acetylates histones H3 and H4 in vitro and exhibits autoacetylation activity
0.107
YNL129W - NRK1
Nicotinamide riboside kinase, catalyzes the phosphorylation of nicotinamide riboside and nicotinic acid riboside in salvage pathways for NAD+ biosynthesis
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.106
YDR309C - GIC2
Redundant rho-like GTPase Cdc42p effector; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region; GIC2 has a paralog, GIC1, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.106
YOL029C - YOL029C
Putative protein of unknown function; identified as interacting with Hsc82p and Hsp82p in high-throughput two-hybrid screens
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.106
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YOR079C - ATX2, YOR29-30
Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation
0.106
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YOR163W - DDP1
Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; high specificity for diadenosine hexa- and pentaphosphates; contains endopolyphosphatase activity with a high affinity for polyphosphates, an activity also observed for its human DIPP homologs; possesses mRNA decapping activity; nudix hydrolase family member; protein abundance increases in response to DNA replication stress
0.106
YJR082C - EAF6
Subunit of the NuA4 acetyltransferase complex that acetylates histone H4 and NuA3 acetyltransferase complex that acetylates histone H3
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.104
YGL195W - GCN1, AAS103, NDR1
Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.104
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YOR009W - TIR4
Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock
0.104
YBL095W - YBL095W
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.103
YHR146W - CRP1
Protein that binds to cruciform DNA structures; CRP1 has a paralog, MDG1, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.103
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YPR075C - OPY2
Integral membrane protein that acts as a membrane anchor for Ste50p; involved in the signaling branch of the high-osmolarity glycerol (HOG) pathway and as a regulator of the filamentous growth pathway; overproduction blocks cell cycle arrest in the presence of mating pheromone; relocalizes from vacuole to plasma membrane upon DNA replication stress
0.103
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YPR151C - SUE1
Mitochondrial protein required for degradation of unstable forms of cytochrome c
0.103
YGR243W - FMP43, MPC3
Highly conserved subunit of mitochondrial pyruvate carrier; more highly expressed in glucose-containing minimal medium than in lactate-containing medium; expression regulated by osmotic and alkaline stresses; protein abundance increases in response to DNA replication stress; FMP43 has a paralog, MPC2, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.102
YLR023C - IZH3
Membrane protein involved in zinc ion homeostasis, member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.101
YLR385C - SWC7, AWS1
Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.101
YLR406C - RPL31B, L31e, YL28, L34B, L31B
Ribosomal 60S subunit protein L31B; associates with karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers lethality; homologous to mammalian ribosomal protein L31, no bacterial homolog; RPL31B has a paralog, RPL31A, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.101
YBR005W - RCR1, SSH6
Protein of the ER membrane involved in cell wall chitin deposition; may function in the endosomal-vacuolar trafficking pathway, helping determine whether plasma membrane proteins are degraded or routed to the plasma membrane; RCR1 has a paralog, RCR2, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.101
YDR351W - SBE2
Protein required for bud growth; involved in transport of cell wall components from the Golgi to the cell surface; SBE2 has a paralog, SBE22, that arose from the whole genome duplication
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.101
YLR296W - YLR296W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
0.100
YOL030W - GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YOL084W - PHM7
Protein of unknown function; expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole; protein abundance increases in response to DNA replication stress
0.100