17 genetic interactions and 58 correlations retrieved

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Genetic interactions
Correlations

Negative genetic interactions

Query gene Array gene SGA score p-value
YMR307W - GAS1, GGP1, CWH52
Beta-1,3-glucanosyltransferase, required for cell wall assembly and also has a role in transcriptional silencing; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor; also found at the nuclear periphery
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.28 4.6e-19
YDR516C - EMI2
Non-essential protein of unknown function; required for transcriptional induction of the early meiotic-specific transcription factor IME1; required for sporulation; expression regulated by glucose-repression transcription factors Mig1/2p; EMI2 has a paralog, GLK1, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.26 1.2e-03
YGR099W - tel2-7
Subunit of the ASTRA complex, involved in chromatin remodeling; subunit of the telomere cap complex DNA-binding protein specific to single-stranded yeast telomeric DNA repeats, required for telomere length regulation and telomere position effect; involved in the stability or biogenesis of PIKKs such as TORC1
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.26 2.6e-03
YJL176C - SWI3, TYE2
Subunit of the SWI/SNF chromatin remodeling complex; SWI/SNF regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; relocates to the cytosol under hypoxic conditions
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.23 1.8e-11
YBR087W - rfc5-1
Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.20 3.8e-06
YBL079W - NUP170, NLE3
Subunit of the inner ring of the nuclear pore complex (NPC); contributes to NPC assembly and nucleocytoplasmic transport; both Nup170p and NUP157p are similar to human Nup155p; NUP170 has a paralog, NUP157, that arose from the whole genome duplication
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.19 3.1e-12
YPL158C - AIM44, GPS1
Protein that regulates Cdc42p and Rho1p; functions in the late steps of cytokinesis and cell separation; sustains Rho1p at the cell division site after actomyosin ring contraction; inhibits the activation of Cdc42-Cla4 at the cell division site to prevent budding inside the old bud neck; transcription is regulated by Swi5p; null mutant displays elevated frequency of mitochondrial genome loss; relocalizes from bud neck to cytoplasm upon DNA replication stress
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.19 3.3e-04
YOL135C - med7-163
Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.18 9.5e-03
YER052C - HOM3, THR3, SIL4, BOR1
Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.18 1.9e-02
YCL008C - STP22, VPL15, VPS23
Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.17 1.5e-08
YOR025W - HST3
Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.17 1.9e-03
YPR029C - APL4
Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.17 3.2e-02
YAL002W - VPS8, VPL8, VPT8, FUN15
Membrane-binding component of the CORVET complex; involved in endosomal vesicle tethering and fusion in the endosome to vacuole protein targeting pathway; interacts with Vps21p; contains RING finger motif
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.17 3.5e-03
YPL032C - SVL3
Protein of unknown function; mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; relocalizes from bud neck to cytoplasm upon DNA replication stress; SVL3 has a paralog, PAM1, that arose from the whole genome duplication
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
-0.16 2.6e-02

Positive genetic interactions

Query gene Array gene SGA score p-value
YDR197W - CBS2, CBP7
Mitochondrial translational activator of the COB mRNA; interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.37 8.1e-09
YDR148C - KGD2
Dihydrolipoyl transsuccinylase, component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.21 7.0e-05
YGL167C - PMR1, SSC1, LDB1, BSD1
High affinity Ca2+/Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting and processing; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.13 7.4e-04

Correlations

Gene 1 Gene 2 Correlation
YGR196C - FYV8
Protein of unknown function, required for survival upon exposure to K1 killer toxin
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.173
YGL059W - PKP2
Mitochondrial protein kinase; negatively regulates activity of the pyruvate dehydrogenase complex by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp1p and phosphatases Ptc5p and Ptc6p; relocalizes from mitochondrion to cytoplasm upon DNA replication stress
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.164
YDR540C - IRC4
Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.161
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YPL156C - PRM4
Pheromone-regulated protein proposed to be involved in mating; predicted to have 1 transmembrane segment; transcriptionally regulated by Ste12p during mating and by Cat8p during the diauxic shift
0.155
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YKL062W - MSN4
Transcriptional activator; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression; MSN4 has a paralog, MSN2, that arose from the whole genome duplication
0.152
YGR121C - MEP1, AMT1
Ammonium permease; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation; MEP1 has a paralog, MEP3, that arose from the whole genome duplication
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.146
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YPR150W - YPR150W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene SUE1/YPR151C
0.145
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YJR099W - YUH1
Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p
0.144
YDR541C - YDR541C
Putative dihydrokaempferol 4-reductase
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.138
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YKL216W - URA1
Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid
0.134
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YPL035C - YPL035C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YPL034W; YPL035C is not an essential gene
0.132
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YLR377C - FBP1, ACN8
Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; interacts with Vid30p
0.128
YGR217W - CCH1
Voltage-gated high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones; interacts and co-localizes with Mid1p, suggesting Cch1p and Mid1p function together
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.127
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YNL111C - CYB5
Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; acts as an electron donor to support sterol C5-6 desaturation
0.126
YGL199C - YGL199C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YIP4/YGL198W
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.125
YBR014C - GRX7
Cis-golgi localized monothiol glutaredoxin; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; does not bind metal ions; GRX7 has a paralog, GRX6, that arose from the whole genome duplication
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.124
YCL060C - YCL060C, YCL060C
S-phase checkpoint protein required for DNA replication; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; protects uncapped telomeres
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.124
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YJL130C - URA2
Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP
0.122
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YMR255W - GFD1
Coiled-coiled protein of unknown function; identified as a high-copy suppressor of a dbp5 mutation; protein abundance increases in response to DNA replication stress
0.122
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YPR013C - CMR3
Putative zinc finger protein; YPR013C is not an essential gene
0.122
YGL224C - SDT1, SSM1
Pyrimidine nucleotidase; overexpression suppresses the 6-AU sensitivity of transcription elongation factor S-II, as well as resistance to other pyrimidine derivatives; SDT1 has a paralog, PHM8, that arose from the whole genome duplication
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.120
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YHL035C - VMR1
Vacuolar membrane protein; involved in multiple drug resistance and metal sensitivity; ATP-binding cassette (ABC) family member involved in drug transport; potential Cdc28p substrate; induced under respiratory conditions; VMR1 has a paralog, YBT1, that arose from the whole genome duplication
0.119
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YHR076W - PTC7
Type 2C protein phosphatase (PP2C); alternatively spliced to create two mRNA isoforms; protein from spliced form localizes to the mitochondria while the one from the unspliced form is localized to the nuclear envelope
0.119
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YML107C - PML39
Protein required for nuclear retention of unspliced pre-mRNAs along with Mlp1p and Pml1p; anchored to nuclear pore complex via Mlp1p and Mlp2p; found with the subset of nuclear pores farthest from the nucleolus; may interact with ribosomes
0.118
YAL053W - FLC2, HUF2
Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; FLC2 has a paralog, YOR365C, that arose from the whole genome duplication
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.117
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YGR289C - MAL11, MALT, AGT1
Inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; broad substrate specificity that includes maltotriose; required for isomaltose utilization
0.117
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YOR167C - RPS28A, S28e, YS27, S33A, S28A, RPS33A
Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S28, no bacterial homolog; RPS28A has a paralog, RPS28B, that arose from the whole genome duplication
0.117
YGR109C - CLB6
B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1; CLB6 has a paralog, CLB5, that arose from the whole genome duplication
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.116
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YLR228C - ECM22
Sterol regulatory element binding protein; regulates transcription of sterol biosynthetic genes; contains Zn[2]-Cys[6] binuclear cluster; relocates from intracellular membranes to perinuclear foci on sterol depletion; ECM22 has a paralog, UPC2, that arose from the whole genome duplication
0.116
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YOR345C - YOR345C
Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene REV1; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2
0.116
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YLR294C - YLR294C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene ATP14
0.115
YDR519W - FPR2, FKB2
Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase); binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking; relocalizes from nucleus to vacuole upon DNA replication stress
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.114
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YIL037C - PRM2
Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; required for efficient nuclear fusion
0.113
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YJL201W - ECM25
Non-essential protein of unknown function; promoter contains a consensus binding sequence for factor Abf1p
0.113
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YMR096W - SNZ1
Protein involved in vitamin B6 biosynthesis; member of a stationary phase-induced gene family; coregulated with SNO1; interacts with Sno1p and with Yhr198p, perhaps as a multiprotein complex containing other Snz and Sno proteins
0.113
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YPL001W - HAT1, KAT1
Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair
0.113
YBR041W - FAT1
Very long chain fatty acyl-CoA synthetase and long chain fatty acid transporter; activates imported fatty acids with a preference for very long lengths (C20-C26); has a separate function in the transport of long chain fatty acids
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.110
YGR169C - PUS6
tRNA:pseudouridine synthase, catalyzes the conversion of uridine to pseudouridine at position 31 in cytoplasmic and mitochondrial tRNAs; mutation of Asp168 to Ala abolishes enzyme activity; not essential for viability
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.109
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YLR414C - YLR414C
Plasma membrane protein with a role in cell wall integrity; co-localizes with Sur7p in punctate membrane patches; null mutant displays decreased thermotolerance; transcription induced upon cell wall damage and metal ion stress
0.109
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YMR044W - IOC4
Member of a complex (Isw1b) with Isw1p and Ioc2p; interacts directly with H3K36me3 nucleosomes through its PWWP domain to recruit the Isw1b complex to open reading frames in a Set2p-dependent manner; Isw1b exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing
0.109
YCL061C - MRC1, YCL060C
S-phase checkpoint protein required for DNA replication; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; protects uncapped telomeres
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.107
YDR538W - PAD1, POF1
Phenylacrylic acid decarboxylase, confers resistance to cinnamic acid, decarboxylates aromatic carboxylic acids to the corresponding vinyl derivatives; also has mRNA binding activity; homolog of E. coli UbiX
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.107
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YPR095C - SYT1
Guanine nucleotide exchange factor (GEF) for Arf proteins; promotes activation of Arl1p, which recruits Imh1p to the Golgi; involved in vesicular transport; member of the Sec7-domain family; contains a PH domain
0.107
YBR260C - RGD1
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in control of actin cytoskeleton organization
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.106
YDL048C - STP4
Protein containing a Kruppel-type zinc-finger domain; similar to Stp1p, Stp2p; predicted transcription factor; relative distribution to the nucleus increases upon DNA replication stress; STP4 has a paralog, STP3, that arose from the whole genome duplication
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.106
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YHR043C - DOG2
2-deoxyglucose-6-phosphate phosphatase; member of a family of low molecular weight phosphatases, paralogous to DOG1, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed
0.104
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YIL015C-A - YIL015C_A, YIL015C-A
Putative protein of unknown function
0.104
YGR025W - YGR025W
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.103
YDR210W - YDR210W
Predicted tail-anchored plasma membrane protein containing a conserved CYSTM module; related proteins in other organisms may be involved in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.102
YAL059W - ECM1
Pre-ribosomal factor involved in 60S ribosomal protein subunit export; associates with the pre-60S particle; shuttles between the nucleus and cytoplasm
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.102
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YJL083W - TAX4
EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; TAX4 has a paralog, IRS4, that arose from the whole genome duplication
0.102
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YOL035C - YOL035C
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
0.102
YDR111C - ALT2
Catalytically inactive alanine transaminase; expression is repressed in the presence of alanine and repression is mediated by Nrg1p; ALT2 has a paralog, ALT1, that arose from the whole genome duplication
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.101
YDR528W - HLR1
Protein involved in regulation of cell wall composition and integrity and response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; similar to Lre1p, which functions antagonistically to protein kinase A;
HLR1 has a paralog, LRE1, that arose from the whole genome duplication
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.101
YAL004W - YAL004W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene SSA1/YAL005C
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
0.101
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YJL158C - CIS3, CCW5, PIR4, CCW11
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
0.101
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YLR420W - URA4
Dihydroorotase, catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate
0.101
YGR282C - BGL2
Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
YHR132W-A - IGO2
Protein required for initiation of G0 program; prevents degradation of nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway; phosphorylated by Rim15p; GFP protein localizes to the cytoplasm and nucleus; IGO2 has a paralog, IGO1, that arose from the whole genome duplication
0.100