3 genetic interactions and 71 correlations retrieved

Download as Excel file:
Genetic interactions
Correlations

Positive genetic interactions

Query gene Array gene SGA score p-value
YLR314C - cdc3-3
Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble with other septins into rod-like complexes that can associate with other rods to form filament polymers; septin rings at the mother-bud neck act as scaffolds for recruiting factors needed for cell division and as barriers to prevent diffusion of specific proteins between mother and daughter cells
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.14 3.9e-03
YHR116W - COX23
Mitochondrial intermembrane space protein that functions in mitochondrial copper homeostasis, essential for functional cytochrome oxidase expression; homologous to Cox17p; contains twin cysteine-x9-cysteine motifs
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.13 3.5e-08
YFL027C - GYP8
GTPase-activating protein for yeast Rab family members; Ypt1p is the preferred in vitro substrate but also acts on Sec4p, Ypt31p and Ypt32p; involved in the regulation of ER to Golgi vesicle transport
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.12 3.5e-02

Correlations

Gene 1 Gene 2 Correlation
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR085W - YCR085W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
0.174
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR069W - CPR4, SCC3, YCR070W, CYP4
Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway; CPR4 has a paralog, CPR8, that arose from the whole genome duplication
0.148
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR098C - GIT1
Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability
0.148
YCL026C-A - FRM2, YCLX08C
Type II nitroreductase, using NADH as reductant; mutants are defective in fatty acid mediated repression of genes involved in fatty acid biosynthesis indicative of a role in lipid signaling; involved in the oxidative stress response; transcription induction by cadmium and selenite indicates a possible role in the metal stress response; expression induced in cells treated with the mycotoxin patulin
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.147
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YDL061C - RPS29B, S14, YS29, S36B, S29B, YS29B
Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S29 and bacterial S14; RPS29B has a paralog, RPS29A, that arose from the whole genome duplication
0.146
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YPL107W - YPL107W
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YPL107W is not an essential gene
0.145
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCL036W - GFD2, YCD6
Protein of unknown function; identified as a high-copy suppressor of a dbp5 mutation; GFD2 has a paralog, YDR514C, that arose from the whole genome duplication
0.137
YCL001W-A - YCL001W_A
Putative protein of unknown function; YCL001W-A gene has similarity to DOM34 and is present in a region duplicated between chromosomes XIV and III
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.133
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YIR039C - YPS6
Putative GPI-anchored aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance
0.133
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YPL264C - YPL264C
Putative membrane protein of unknown function; physically interacts with Hsp82p; YPL264C is not an essential gene
0.133
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YDL071C - YDL071C, IRC1
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF BDF2/YDL070W
0.130
YCL006C - YCL006C
Deleted ORF, does not encode a protein; this ORF was removed when a sequence update created a stop codon after residue 23
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.127
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YDR351W - SBE2
Protein required for bud growth; involved in transport of cell wall components from the Golgi to the cell surface; SBE2 has a paralog, SBE22, that arose from the whole genome duplication
0.127
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YER066W - YER066W
Putative protein of unknown function; non-essential gene identified in a screen for mutants with decreased levels of rDNA transcription
0.126
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YMR195W - ICY1
Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication
0.126
YBR297W - MAL33, MALR, MAL3R
MAL-activator protein, part of complex locus MAL3; nonfunctional in genomic reference strain S288C
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.125
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YGL067W - NPY1
NADH diphosphatase (pyrophosphatase), hydrolyzes the pyrophosphate linkage in NADH and related nucleotides; localizes to peroxisomes; nudix hydrolase family member
0.125
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YLR095C - IOC2
Member of a complex (Isw1b) with Isw1p and Ioc4p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PHD finger motif
0.124
YBR240C - THI2, phoF, PHO6
Transcriptional activator of thiamine biosynthetic genes; interacts with regulatory factor Thi3p to control expression of thiamine biosynthetic genes with respect to thiamine availability; acts together with Pdc2p to respond to thiaminediphosphate demand, possibly as related to carbon source availability; zinc finger protein of the Zn(II)2Cys6 type
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.122
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YGR287C - YGR287C
Major isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase); required for isomaltose utilization; specificity for isomaltose, alpha-methylglucoside, and palatinose; member of the IMA isomaltase family
0.122
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YHL045W - YHL045W
Putative protein of unknown function; not an essential gene
0.122
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR077C - PAT1, MRT1
Deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; associated with topoisomerase II; functionally linked to Pab1p; forms cytoplasmic foci upon DNA replication stress
0.121
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR087C-A - LUG1, LUG1
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YCR087C-A is not an essential gene
0.121
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YOR298C-A - MBF1, SUF13
Transcriptional coactivator; bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations; protein abundance increases in response to DNA replication stress
0.121
YAL066W - YAL066W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.119
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YDL129W - YDL129W
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; YDL129W is not an essential gene; relative distribution to the nucleus increases upon DNA replication stress
0.118
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YJL136C - RPS21B, S21e, YS25, S26B, S21B
Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S21, no bacterial homolog; RPS21B has a paralog, RPS21A, that arose from the whole genome duplication
0.118
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YOL048C - YOL048C
Protein of unknown function; identified in a screen for mutants with increased levels of rDNA transcription; green fluorescent protein (GFP)-fusion protein localizes to lipid particles; protein abundance increases in response to DNA replication stress
0.118
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YDR191W - HST4
Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
0.117
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YMR122C - YMR122C
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
0.117
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YPR188C - MLC2
Regulatory light chain for the type II myosin, Myo1p; binds to an IQ motif of Myo1p, localization to the bud neck depends on Myo1p; involved in the disassembly of the Myo1p ring
0.117
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YJL141C - YAK1
Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose
0.116
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YFR048W - RMD8
Cytosolic protein required for sporulation
0.114
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YJL212C - OPT1, GSH11, HGT1
Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family
0.114
YBR284W - YBR284W
Putative metallo-dependent hydrolase superfamily protein; similar to AMP deaminases but lacks key catalytic residues and does not rescue purine nucleotide metabolic defect of quadruple aah1 ade8 amd1 his1 mutant; null mutant exhibits longer telomeres, altered Ty mobility, decreased resistance to rapamycin and wortmannin; induced in response to hydrostatic pressure; not an essential gene; YBR284W has a paralog, YJL070C, that arose from the whole genome duplication
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.112
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR083W - TRX3
Mitochondrial thioredoxin, highly conserved oxidoreductase required to maintain the redox homeostasis of the cell, forms the mitochondrial thioredoxin system with Trr2p, redox state is maintained by both Trr2p and Glr1p
0.112
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YMR202W - ERG2, END11
C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis
0.112
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YOL054W - PSH1
E3 ubiquitin ligase that mediates poyubiquitination and degradation of centromere-binding protein Cse4p and prevents Cse4p from mislocalizing to euchromatin; ubiquitylation of Cse4p may be antagonized by Scm3p
0.112
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCL035C - GRX1
Glutathione-dependent disulfide oxidoreductase; hydroperoxide and superoxide-radical responsive, heat-stable, with active site cysteine pair; protects cells from oxidative damage; GRX1 has a paralog, GRX2, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
0.111
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YHR094C - HXT1, HOR4
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting; HXT1 has a paralog, HXT6, what arose from the whole genome duplication
0.111
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YPL072W - UBP16
Deubiquitinating enzyme anchored to the outer mitochondrial membrane, probably not important for general mitochondrial functioning, but may perform a more specialized function at mitochondria
0.111
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCL042W - YCL042W
Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm
0.110
YBR199W - KTR4
Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.109
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YER056C - FCY2, BRA7
Purine-cytosine permease; mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation; relative distribution to the vacuole increases upon DNA replication stress
0.109
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YPR146C - YPR146C
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
0.109
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR024C-A - PMP1
Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p; small single-membrane span proteolipid; forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines; PMP1 has a paralog, PMP2, that arose from the whole genome duplication
0.108
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YDL188C - PPH22, PPH2
Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; protein abundance increases in response to DNA replication stress; PPH22 has a paralog, PPH21, that arose from the whole genome duplication
0.108
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR068W - ATG15, CVT17, AUT5
Lipase required for intravacuolar lysis of autophagic bodies and Cvt bodies; targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway
0.107
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YNR058W - BIO3
7,8-diamino-pelargonic acid aminotransferase (DAPA), catalyzes the second step in the biotin biosynthesis pathway; BIO3 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis
0.107
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR067C - SED4
Integral ER membrane protein that stimulates Sar1p GTPase activity; involved in COPII vesicle budding through disassociation of coat proteins from membranes onto liposomes; binds Sec16p; SED4 has a paralog, SEC12, that arose from the whole genome duplication
0.106
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR102C - YCR102C
Putative protein of unknown function, involved in copper metabolism; similar to C. carbonum toxD gene; member of the quinone oxidoreductase family
0.106
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YHL036W - MUP3
Low affinity methionine permease, similar to Mup1p
0.106
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YJL042W - MHP1
Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins
0.106
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YHR126C - ANS1
Putative GPI protein; transcription dependent upon Azf1p
0.105
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YNL047C - SLM2, LIT1
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; phosphorylated by the TORC2 complex; SLM2 has a paralog, SLM1, that arose from the whole genome duplication
0.105
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YOR139C - YOR139C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SFL1/YOR140W
0.105
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YIR001C - SGN1, RBP29, RBP1
Cytoplasmic RNA-binding protein, contains an RNA recognition motif (RRM); may have a role in mRNA translation, as suggested by genetic interactions with genes encoding proteins involved in translational initiation
0.104
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YOR252W - TMA16, RBF17
Protein of unknown function that associates with ribosomes
0.104
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YPL253C - VIK1
Protein that forms a complex with Kar3p at the spindle pole body; possible regulator of Kar3p function in microtubule-mediated processes; required for sister chromatid cohesion; VIK1 has a paralog, CIK1, that arose from the whole genome duplication
0.104
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR009C - RVS161, SPE161, FUS7, END6
Amphiphysin-like lipid raft protein; interacts with Rvs167p and regulates polarization of the actin cytoskeleton, endocytosis, cell polarity, cell fusion and viability following starvation or osmotic stress
0.103
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YGL002W - ERP6
Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; ERP6 has a paralog, ERP1, that arose from the whole genome duplication
0.103
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YJR124C - YJR124C
Putative protein of unknown function; expression induced under calcium shortage
0.103
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YCR075C - ERS1
Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains
0.102
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YJL055W - YJL055W
Putative protein of unknown function, proposed to be involved in the metabolism of purine and pyrimidine base analogues; deletion mutants are sensitive to HAP and AHA; overexpression confers resistance to 5-FOA and 5-FU
0.102
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YLR126C - YLR126C
Putative glutamine amidotransferase; has Aft1p-binding motif in the promoter; may be involved in copper and iron homeostasis; YLR126C is not an essential protein; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress
0.102
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YMR155W - YMR155W
Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen
0.102
YBR099C - YBR099C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene MMS4
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.101
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YOR016C - ERP4
Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; ERP4 has a paralog, ERP2, that arose from the whole genome duplication
0.101
YBL070C - YBL070C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
0.100
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YER150W - SPI1
GPI-anchored cell wall protein involved in weak acid resistance; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; SPI1 has a paralog, SED1, that arose from the whole genome duplication
0.100
YCL028W - RNQ1, [PIN(+)]
[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
YMR121C - RPL15B, L15e, rp15R, YL10, L15B, L13B
Ribosomal 60S subunit protein L15B; binds to 5.8 S rRNA; homologous to mammalian ribosomal protein L15, no bacterial homolog; RPL15B has a paralog, RPL15A, that arose from the whole genome duplication; relocalizes from nucleus to nucleolus upon DNA replication stress
0.100