DRYGIN is a database of quantitative genetic interactions of S. Cerevisiae derived from the SGA double-mutant arrays conducted in Boone lab at Terrence Donnelly Centre for Cellular and Biochemical Research, University of Toronto.
Current version of DRYGIN is 1.0 (DRYGIN documentation).
Recent news: New Unpublished Genetic Interaction Data available here.
Latest Database statistics
- Total SGA genetic interactions in DRYGIN: 5,482,948
- Total genes screened: 1,711 query (1,672 ORFs) X 3,885 array (3,885 ORFs)
- Updates:
2010-02-10: The database was updated with the latest values from Costanzo et al., 2010.
2010-11-18: The clc1Δ screen was removed because an allele discrepancy was noticed.
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| For description of the database content, please refer to Judice L.Y. Koh, Huiming Ding, Michael Costanzo, Anastasia Baryshnikova, Kiana Toufighi, Gary D. Bader, Chad L. Myers, Brenda J. Andrews, and Charles Boone. DRYGIN: a database of quantitative genetic interaction networks in yeast. Nucleic Acids Research, 2010, Vol. 38, Database issue D502-D507. |
 | Search genes - Query SGA genetic interactions using gene names or orfs. Download interactions or visualize network or clustergram, with genes color-coded according to functional annotations. |
 | Sub-networks - Search and visualize sub-networks of genetic interactions between a group of genes. |
 | Search complexes/pathways - Search and visualize SGA genetic interactions in known protein complexes and pathways. |
 | Overlap with BIOGRID - Search for SGA genetic interactions that overlap with BIOGRID genetic and physical interactions. |
 | Download - Download latest SGA genetic interactions in Cytoscape SIF, tab-delimited, or Java Treeview CDT formats. |
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